Treating Addiction with an Addictive Drug: The Ketamine Paradox - Addiction/Recovery eBulletin

GOOD OR BAD? –

May 29, 2026 – Conclusions: Ketamine represents a promising but still experimental intervention for both refractory depression and selected SUDs. Its clinical use depends on careful patient selection, structured delivery, and integration with psychotherapy.  Although ketamine may redefine treatment paradigms for TRD and addiction, larger-scale trials and long-term safety data are essential to define its role within psychiatric and addiction treatment frameworks.

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