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Jan. 1, 2025 – In your 40s, more health risks begin to pop up, Landsverk explains. “Obesity, diabetes, hypertension and high cholesterol all increase the risk for heart attacks, strokes and small stroke dementia,” she said. If you’re living with any of these conditions, even a small amount of alcohol can further increase your risk of events like heart attacks or strokes, so keep that in mind. Once you hit your 50s, Landsverk says, even moderate drinking can wreak havoc on the body. “Alcohol, besides the vascular damage and dementia risks, increases the risk of breast cancer, esophageal cancer and liver cancer (after disease),” she said. Because cancer risk drastically increases as we age, adding any amount of alcohol into the mix will only further increase that risk. “Plus, as we age, good sleep is more elusive,” Landsverk added. “Substances like caffeine, cigarettes and alcohol all hinder sleep”

In your 60s, you’ll likely begin to feel the effects of moderate drinking on your body. “I can speak from experience: This is the age when tolerance may decrease dramatically,” Landsverk said. “I am healthy. I can ski or swim a mile, but a glass of wine makes me feel ill and slow the next day.”

This, she says, is because older people are more likely to lose the enzyme to metabolize alcohol (alcohol dehydrogenase). “At this point, I can tolerate about one glass a week,” Landsverk noted. “If I had it daily, I would feel sick with just one glass a day. Older people have less reserve in the brain, liver and kidneys. The damage to the brain from even one glass a day is worse [when you’re over 60].”

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