That’s Depressing –

Jan. 5, 2020 – Many antidepressants lower libido and interfere with sexual pleasure. There is even a medical name for this condition: treatment emergent sexual dysfunction (TESD). The official prescribing information for drugs like fluoxetine minimizes this problem. For example, the DailyMed data on Prozac (fluoxetine) suggests an incidence of 3% to 11%. Studies in healthy volunteers, on the other hand, indicate that between 50% and 80% of people report sexual dysfunction (Journal of Clinical Medicine, Oct. 7, 2019).

A few antidepressants may be less likely to flatten sex drive. Ask your doctor whether bupropion or mirtazapine would be an option for you. They act on different neurochemicals than the selective serotonin reuptake inhibitors such as fluoxetine.

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