PAIN IS A PAIN –

Oct. 2022 – “We are interested in the use of this and related molecules to manage chronic pain in the clinic. Obviously, the interest is in using the compounds by themselves, given that they do not produce the sedation characteristic of dexmedetomidine, which is a great drug, but one that is largely limited to ICU situations where sedation is an advantage. Of particular interest is the possibility of combining the new ligands with low doses of opioids, producing at least additive, if not synergistic, analgesic effects without the adverse side effects typically associated with opioids.”

more@MedicalNewsToday