Oct. 28, 2021 – “Fluvoxamine may reduce the production of inflammatory molecules called cytokines, that can be triggered by SARS-CoV-2 infection,” Reiersen said in a statement. The drug may also reduce blood platelets, which may affect the clotting effects of coronavirus infection. Reierson and colleagues gave 741 volunteers with Covid-19 100 mg of fluvoxamine twice a day for 10 days while 756 volunteers got a placebo.
Among the patients who got fluvoxamine, 79 — or about 11% — needed treatment in an ER or hospital room compared to nearly 16% of those given placebos. It was a 5% decrease in absolute risk and a 32% decrease in relative risk.
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