April 9, 2024 – New treatments for addiction are urgently needed. 107,941 people died from drug overdoses in 2022, an age-adjusted rate of 32.6 deaths per 100,000 people. The rate has nearly quadrupled since 2002. Researchers have made it important to consider the treatment potential of ibogaine and its derivatives.
lbogaine is one of the psychoactive indole alkaloids found in the West African shrub Tabernanthe iboga. Since its introduction to Western medicine, the psychedelic agent has been used as an adjunct for psychotherapy and also for its anti-addiction properties. In contrast, current treatments for opioid use disorder (OUD) as well as for dependence on cocaine and methamphetamine, as reviewed by Yale’s Brian Fuerhlein and Jean Lud Cadet of the National Institute on Drug Abuse(NIDA), are limited in efficacy, don’t accelerate brain recovery, and don’t return people to where they were before drug use became a raging addiction…
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