MAY 18, 2019 – Describing caffeine as the “most widely consumed psychoactive drug,” Stafford said the findings suggest that changes in the ability to detect smells could be a useful index of drug dependency. The study authors said their work could lead to new methods of aversion therapy to treat addiction to substances with a distinct smell, such as tobacco and marijuana.
“We have known for some time that drug cues [for example, the smell of alcohol] can trigger craving in users, but here we show with a mildly addictive drug, that craving might be linked to an increased ability to detect that substance,” Stafford explained. Previous research revealed that people who were trained to associate an odor with something unpleasant later showed greater dislike of that odor. That suggests a possible model for conditioned odor aversion, the researchers said.
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